Embryo Kinetics and Stimulation Protocol: Recombinant Follicle Stimulating Hormone (FSH) Versus Human FSH

IVI Madrid

Status: Terminated

Conditions: Embryo Kinetics

Treatments: Procedure: Stimulation with recombinant FSH; Procedure: Stimulation with human FSH

Study type: Interventional

Funder types: Other

Identifiers

NCT01678651

MAD-NB-08-2012-01

Details and patient eligibility

About

Different kinetics markers have been proposed to select embryos with higher implantation rates. The effect of external factors on these markers, such as the stimulation protocol should be analyzed. There are two different types of FSH that are commonly used for in vitro fertilization (IVF) in egg donation cycles, recombinant FSH and human FSH. The effect of each kind of hormone on embryo kinetcis is still unknown. The aim of this study is to observe if there is a difference in embryo kinetics and morphology as well as oocyte morphological parameters between the two types of FSH and therefore to analyze if such markers can be used despite of the stimulation protocols chosen.

Enrollment: 80 patients

Sex: All

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

•Egg donation cycles with more than 8MII in oocyte retrieval day

Exclusion criteria

• Male factor
• Uterine malformations
• genetic alterations

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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80 participants in 2 patient groups

Human FSH

Active Comparator group

Description:

Human FSH

Treatment:

Procedure: Stimulation with human FSH

Recombinant FSH

Active Comparator group

Description:

Recombinant FSH

Treatment:

Procedure: Stimulation with recombinant FSH