Emergence Agitation in Adult Patients After Intracranial Surgery

Capital Medical University

Status: Completed

Conditions: Postoperative Care; Intensive Care, Surgical; Neurosurgery

Treatments: Procedure: Anesthesia recovery after intracranial surgery

Study type: Observational

Funder types: Other

Identifiers

NCT02318199

KY2014-034-01

Details and patient eligibility

About

Emergence agitation is a frequent complication that can have serious consequences during recovery from general anesthesia. However, agitation has been poorly investigated in patients after craniotomy. In this prospective multicenter cohort study, adult patients will be enrolled after craniotomy and emergence agitation will be evaluated. The incidence, risk factors and outcome will be investigated.

Enrollment: 400 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Both supratentorial and infratentorial intradural cranial operations

Exclusion criteria

• Unarousable state (SAS=1) during the first 24 hours after the operation
• Interval longer than 24 hours between the end of the surgery and neurosurgical ICU admission

Trial design

400 participants in 2 patient groups

Agitation group

Description:

Patient is evaluated by the sedation-agitation scale (SAS) during the anesthesia recovery after intracranial surgery under general anesthesia. SAS equals to 5-7 during the first 12 hours after surgery.

Treatment:

Procedure: Anesthesia recovery after intracranial surgery

Non-agitation group

Description:

Patient is evaluated by the sedation-agitation scale (SAS) during the anesthesia recovery after intracranial surgery under general anesthesia. SAS equals to 1-4 during the first 12 hours after surgery.

Treatment:

Procedure: Anesthesia recovery after intracranial surgery