Emergency Department CT Scanning for Appendicitis

WellSpan Health

Status: Completed

Conditions: Appendicitis

Treatments: Other: Omnipaque

Study type: Interventional

Funder types: Other

Identifiers

NCT00734825

0607012

Details and patient eligibility

About

The purpose of this study is to compare IV contrast only vs. IV and oral contrast Computed Tomography (CT) for the diagnosis of acute appendicitis in adult patients in our emergency department. A secondary purpose will be to design a specific CT for appendicitis protocol at our institution at the conclusion of this study.

Enrollment: 244 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years and older who present to the York Hospital Emergency Department with signs and symptoms suggestive of acute appendicitis, but in whom the diagnosis remains unclear as determined by an attending emergency physician or consulting surgeon and in which a CT scan is needed to further assist in the diagnosis

Exclusion criteria

• pregnant patients
• patients with known IV dye or oral contrast allergy
• patients in whom acute appendicitis is not the primary diagnosis
• patients with renal insufficiency that may have significant adverse effect from IV dye

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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244 participants in 2 patient groups

1

Active Comparator group

Description:

IV contrast

Treatment:

Other: Omnipaque

2

Active Comparator group

Description:

IV contrast and oral contrast

Treatment:

Other: Omnipaque