ClinicalTrials.Veeva

Menu

Empirical Mode Decomposition in the Electroencephalogram

National Taiwan University logo

National Taiwan University

Status

Completed

Conditions

Depth of Anesthesia

Study type

Observational

Funder types

Other

Identifiers

NCT03303443
201508007RIN

Details and patient eligibility

About

Bispectral index (BIS), a standard monitor for perioperative monitor of patient's conscious level, is a noninvasive medical technique for monitoring and recording the electrical activity of brain.

Full description

The electroencephalogram and BIS data have lots of information. Fourier transformation to decompose EEG was first applied on the EEG signaling until now. The disadvantages of Fourier transformation is hard to deal with physical signals, which was modulated by autonomic system and factors. The Hilbert-Huang transform (HHT) was proposed to decompose EEG signal into intrinsic mode functions (IMF) since 2004. HHT can obtain instantaneous frequency data and work well for data that is nonstationary and nonlinear. HHT have been applied for wild ranges, not only in the analysis of arrhythmia for medical and public health fields, but also in the earthquake detection and earth physics detection...etc.

The relationship between frontal EEG patterns and general anesthesia remain poorly understood. It can only say that the increase in frontal EEG power and shift power to lower frequencies during general anesthesia from publications. The investigators are going to compare the EEG signal between generations, try to find the difference in aging using empirical mode decomposition method.

Enrollment

60 patients

Sex

All

Ages

20 to 80 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  1. 20-40y/o or over 60y/o
  2. Scheduled for low risk general anesthesia
  3. Suitable for surgery after interviewed by anesthesiologist

Exclusion criteria

  1. Not suitable for general anesthesia
  2. High risk patient
  3. Allergic to the EEG sensor

Trial design

60 participants in 2 patient groups

Younger
Description:
20-40 years old patients
Elderly
Description:
over 60 years old patients

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2026 Veeva Systems