Empyema Following Pneumonectomy for Non Small Cell Lung Cancer (NSCLC)

University Hospital, Gasthuisberg

Status: Completed

Conditions: Lung Cancer; Non Small Cell Lung Cancer

Study type: Observational

Funder types: Other

Identifiers

NCT01837186

EMPY2013

Details and patient eligibility

About

Empyema following pneumonectomy for Non Small Cell Lung Cancer (NSCLC) is a known problem that occurs in about 2% of pneumonectomy patients.

Full description

The development of an empyema following pneumonectomy is a devastating complication, especially if associated with an underlying fistula. Whilst the perioperative mortality of pneumonectomy overall is now less than 5%, this rises to around 25% when complicated by empyema, and about 50% when associated with fistula. In addition, there is the morbidity and social cost of long-term drainage, chronic sepsis and often multiple operations.

Enrollment: 600 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Pneumonectomy for NSCLC

Exclusion criteria

• Pneumonectomy for other reasons (infectious pathology, trauma, mesothelioma, ...)

Trial design

600 participants in 2 patient groups

EFP

Description:

Empyema following pneumonectomy

nEFP

Description:

No empyema following pneumonectomy