Enabling Microbiomics- Driven Personalized Nutrition (EMPOWER)

Mayo Clinic

Status: Invitation-only

Conditions: Functional Dyspepsia; Diarrhea; Celiac Disease; Inflammatory Bowel Disease (IBD); Microbiome; UC - Ulcerative Colitis; Crohn's Disease; Constipation; Irritable Bowel Syndrome (IBS); Microscopic Colitis

Study type: Observational

Funder types: Other

Identifiers

NCT06657001

24-007049

Details and patient eligibility

About

The goal of this observational research study is to determine how diet contributes to various gastrointestinal related conditions.

The main question investigators aim to answer is:

Are host genetics, diet, and microbiome all important determinants of GI disorders, and how their relative contribution varies among individuals and populations.

Enrollment: 4,001 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age greater than or equal to 18 years

• Gastrointestinal patients with or without genomic sequencing results available for the following cohorts:

  • Inflammatory Bowel Disease (IBD)
  • Irritable Bowel Syndrome (IBS)
  • Crohn's Disease
  • Celiac Disease
  • Diarrhea
  • Constipation

• Healthy age and sex matched controls with or without genomic sequencing results available

  o Control is defined as patients without gastrointestinal disease or no symptoms at time of sampling

• Able to provide written, informed consent

• Participant has a smartphone device with access to internet connection

Exclusion criteria

• Patients with cognitive impairment
• Active use of antibiotics at the time of stool collection

Trial design

4,001 participants in 1 patient group

GI Disorders

Description:

Inflammatory Bowel Disease, Irritable Bowel Syndrome, Crohn's Disease, Celiac Disease, Diarrhea, Constipation