Ending Transmission of HIV, HCV, and STDs and Overdose in Rural Communities of People Who Inject Drugs (ETHIC)

The University of Chicago

Status: Completed

Conditions: Opioid-use Disorder; Hepatitis C; HIV; Injection Drug Use

Treatments: Behavioral: Referral to harm reduction services

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT04427202

4UH3DA044829-03 (U.S. NIH Grant/Contract)

IRB17-1630

Details and patient eligibility

About

This study will evaluate the referral to harm reduction services (HRS) including syringe services, naloxone overdose prevention, substance use treatment referral, HIV, HCV, and STD testing and referral and linkage to care through capacity building of existing programs through client services data.

Full description

This is a prospective longitudinal Type 1 Hybrid Implementation Effectiveness Study on the expansion of harm reduction services for people who inject drugs (PWID) and people who use opioids (PWUO) residing in high risk areas of rural southern Illinois. This study record describes one component of the larger Ending transmission of HIV, HCV, and STDs and overdose in rural communities of people who inject drugs (ETHIC) study Community Response Plan (CRP) framework, specifically the expansion of harm reduction services intervention (HRS). The aim is to assess the effectiveness of expansion of evidenced based harm reduction services through our CRP framework comprising: a) geographically targeted recruitment based on hot spot and vulnerability analyses, b) community engagement, c) recruitment via Respondent Driven Sampling (RDS), d) expanded surveillance for HIV and HCV, and e) concomitant HCV and opioid use treatment capacity expansion through the Extension of Community Healthcare Outcomes (ECHO) model. Examination of facilitators and barriers impacting implementation of service delivery is evaluated through mixed methods process evaluation. The Type 1 Hybrid design is supported by conditions including the existing evidence based for benefits and minimal harm of "harm reduction services" and strong base for applicability of this intervention in the study setting (ie rural opioid use)

Enrollment: 306 patients

Sex: All

Ages: 15+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 15 years of age and older
• Injected any drug in the past 30 days
• Used any opioids non-medically in the past 30 days
• English speaking
• Able to provide informed consent at the time of the study visit

Exclusion criteria

• Less than 15 years of age
• Not injected any drug in the past 30 days
• Not used any opioids non-medically in past 30 days
• Non-English speaking
• Has not injected any opioid drug to get high in the past 30 days
• Unable to provide informed consent at the time of the study visit

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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306 participants in 1 patient group

Referral to harm reduction services

Other group

Description:

Participants will be taken through the study survey and interview, blood and urine toxicology testing and given a referral to a harm reduction organization.

Treatment:

Behavioral: Referral to harm reduction services