Endo-Band: Endoscopic Band Ligation for Weight Loss

El Katib Hospital

Status: Enrolling

Conditions: Obesity

Treatments: Device: Endoscopic Band Ligation

Study type: Interventional

Funder types: Other

Identifiers

NCT04431232

MohamedAbeid1

Details and patient eligibility

About

To the best of our knowledge, this is the first study to use endoscopic band ligation for weight loss. All ligatures will be performed in the gastric body starting at the distal body; 5 parallel rows, with the last one in the proximal body.The entire procedure can be completed in 30 min. Oxygen is used for endoscopic air insufflation.Endoscopy is performed using propofol for sedation.

Full description

The idea of band ligation of the gastric body is to induce multiple gastric ulcers that forms a fibrotic scars which can lead to marginal narrowing of the lumen; same as that occurred in the esophagus following band ligation of esophageal varices or in the antrum following band ligation of GAVE.

Enrollment: 5 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI > 27

Exclusion criteria

• Any contraindication for endoscopy
• Any gastric bleeding lesions
• Uncontrolled use of anticoagulants or NSAID's

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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5 participants in 1 patient group

Band Ligation

Experimental group

Description:

Band ligation of gastric body for weight loss

Treatment:

Device: Endoscopic Band Ligation