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Endobronchial Ultrasound-Guided Transbronchial Needle-Aspiration With Suction in Obtaining Samples From Patients With Suspected Nodal Metastatic Lung Cancer (EBUS-Suction)

The Ohio State University logo

The Ohio State University

Status

Active, not recruiting

Conditions

Lung Carcinoma

Treatments

Procedure: Bronchoscopy
Procedure: Ultrasound-Guided Transbronchial Needle Aspiration

Study type

Interventional

Funder types

Other

Identifiers

NCT04116970
OSU-18164 (Other Identifier)
NCI-2018-02965 (Registry Identifier)

Details and patient eligibility

About

This trial studies how well endobronchial ultrasound-guided transbronchial needle-aspiration (EBUS-TBNA) with suction works in obtaining samples from patients with suspected lung cancer that has spread to the nodal. EBUS-TBNA samples obtained with additional suction may help to improve material-amounts and decrease blood contamination in the samples.

Full description

PRIMARY OBJECTIVES:

I. To evaluate if suction applied with a vacuum syringe during EBUS-TBNA sampling helps to obtain more material for molecular analyses.

OUTLINE:

Patients undergo bronchoscopy with EBUS-TBUA first without and then with applied vacuum.

Enrollment

50 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Computed tomography (CT)-scan finding suspicious for lung cancer with nodal metastases
  • Clinically stable to undergo diagnostic workup by bronchoscopy with endobronchial ultrasound

Exclusion criteria

  • Pregnant female
  • Minors
  • Prisoners
  • Patients with contraindication for EBUS such as non-reversible anticoagulation

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

50 participants in 1 patient group

Diagnostic (bronchoscopy with EBUS-TBNA with/without vacuum)
Experimental group
Description:
Patients undergo bronchoscopy with EBUS-TBUA first without and then with applied vacuum.
Treatment:
Procedure: Ultrasound-Guided Transbronchial Needle Aspiration
Procedure: Bronchoscopy

Trial documents
1

Trial contacts and locations

1

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Central trial contact

The Ohio State University Comprehensive Cancer Center

Data sourced from clinicaltrials.gov

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