Endocervical Evaluation With the Curette Versus Cytobrush for the Diagnosis of Dysplasia of the Uterine Cervix

University Hospitals (UH)

Status: Completed

Conditions: Cervical Dysplasia

Treatments: Procedure: Curette v/s endocervical brush

Study type: Interventional

Funder types: Other

Identifiers

NCT01435590

CER 11-029

Details and patient eligibility

About

OBJECTIVE: to compare endocervical brushing with endocervical curettage with respect to diagnostic and patient discomfort.

METHOD: women referred to colposcopy because of abnormal Papanicolaou tests will be randomized to endocervical sampling with either a metal curette (endocervical curettage -ECC) or and endocervical brush. All samples will be submitted for histological study.

Enrollment: 180 estimated patients

Sex: Female

Ages: 21 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• French-speaking
• 21 years or older
• Attending our colposcopy clinic
• Need for endocervical evaluation
• Full autonomy or capacity to understand the procedures

Exclusion criteria

• Pregnancy
• Absence of uterus
• History of DES exposure in utero

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind