Endocrine Determinants of Renal Function in Patients With Hypoparathyroidism (ENDORSE)

San Donato Group (GSD)

Status: Completed

Conditions: Hypoparathyroidism

Treatments: Diagnostic Test: Blood sample and urine collection

Study type: Observational

Funder types: Other

Identifiers

NCT06449729

BP 11006333

Details and patient eligibility

About

Endocrine determinants of renal function in patients with hypoparathyroidism on conventional treatment: a cross-sectional study (ENDORSE)

Enrollment: 46 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• age ≥ 18 years
• diagnosis of chronic (≥ 1 year) post-surgical and autoimmune hypoparathyroidism, as established with undetectable or insufficient PTH concentration in relation to the presence of hypocalcemia
• patients being treated with calcitriol or alfacalcidiol
• patients able to sign the written informed consent

Exclusion criteria

• pregnancy
• severe renal failure requiring dialysis treatment
• macroproteinuria
• use of antihypertensive drugs such as thiazides, ACE inhibitors, sartans, beta and alpha blockers, and antialdosterone drugs
• pazients affected by diabetes mellitus- insulin-treated