Endocrine Outcome of Surgery for Pituitary Adenoma

University of Ulm

Status: Terminated

Conditions: Pituitary Adenoma

Treatments: Procedure: Microsurgical resection; Procedure: Endoscopic resection

Study type: Interventional

Funder types: Other

Identifiers

NCT03515603

EndOSPA

Details and patient eligibility

About

Prospective and randomized compare between microsurgical and endoscopic transsphenoidal MRI assisted resection of pituitary adenomas.

Full description

The main aim of the study is to compare microsurgical and endoscopic transsphenoidal surgery and to determine endocrine outcome. Secondary extent of resection and quality of life will be evaluated.

Enrollment: 36 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Suspected symptomatic or progressively growing pituitary adenoma
• Informed consent

Exclusion criteria

• Prolactinoma
• No follow-up possible
• Emergency surgery without informed consent or without intraoperative MRI

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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36 participants in 2 patient groups

microsurgical technique

Active Comparator group

Treatment:

Procedure: Microsurgical resection

endoscopic technique

Active Comparator group

Treatment:

Procedure: Endoscopic resection