Endodontic Medications for Irreversible Pulpitis: Articaine or Eugenol?

University Hospital, Strasbourg, France

Status: Completed

Conditions: Operative Dentistry; Toothaches; Pulpitides; Endodontic Inflammation

Treatments: Drug: Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne; Drug: Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol

Study type: Observational

Funder types: Other

Identifiers

NCT03472456

6953

Details and patient eligibility

About

The objective of the study is to determine which of the two commonly used endodontic medications (Eugenol VS Articaine) is most effective in controlling postoperative pain in irreversible pulpitis of the mature permanent tooth in adults. To do so, an assessment of the pain felt by patients will be carried out a few days apart. The supposed results are that the medications are equivalent in terms of effectiveness on the pain, but could then present different economic arguments

Full description

In irreversible pulpitis of the mature permanent tooth, the enrolled patients receive endodontic medications (Eugenol or Articaine) in order to determine which one is the more efficient to control the pain.

These patients would have received the same medication without this study. That's why this is an obsevationnal study.

Enrollment: 100 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patient, major, affiliated to a social health insurance scheme
• Patient having agreed to participate in the study
• Urgent consultant patient for irreversible pulpitis
• Patient understanding French

Exclusion criteria

• Refusal of the patient to participate in the study
• Impossibility of performing the surgical procedure
• Impossibility to give the subject information enlightened (difficulty of understanding ...)
• Subject under the protection of justice, or under guardianship
• General contraindication to endodontic treatment in 2 sessions (high risk of infectious endocarditis, for example)
• Chronic intake of analgesic drugs

Trial design

100 participants in 2 patient groups

Articaïne

Treatment:

Drug: Implementation of a pulp medication in compliance with the dental emergency management protocol: articaïne

Eugénol

Treatment:

Drug: Implementation of a pulp medication in compliance with the dental emergency management protocol: eugenol