Endometrial Gene Expression Profile in Controlled Ovarian Stimulation Cycles With Premature Luteinization

Instituto Valenciano de Infertilidad, IVI VALENCIA

Status: Completed

Conditions: Premature Luteinization

Treatments: Procedure: endometrial biopsy

Study type: Interventional

Funder types: Other

Identifiers

NCT00447850

VLC-EL-1006- 307-2

Details and patient eligibility

About

Previous studies have suggested that premature luteinization (PL)during controlled ovarian stimulation (COS) decreases the implantation rate due to a negative effect on the endometrium receptivity. This study aims to describe the impact on endometrial gene expression of PL in GnRH antagonist and GnRH agonist cycles.

Sex: Female

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Oocyte donors
• Age between 18-35 years old
• BMI 18-29
• NORMOGONADOTROPHICS
• PROGESTERONE ≥ 1.2 ng/ml on hCG day

Exclusion criteria

• PolyCystic Ovarian Syndrome (PCOS)
• Endometriosis