Endometrial Priming for Embryo Transfer

Parc de Salut Mar

Status and phase: Completed; Phase 4

Conditions: Sterility

Treatments: Drug: Oral strogen; Drug: Transdermal strogen

Study type: Interventional

Funder types: Other

Identifiers

NCT01430650

UREP-PREPENDO-2010

Details and patient eligibility

About

The aim of this trial is compare two different endometrial priming protocols

• women that receive oral estrogens
• women that receive transdermal estrogens

Enrollment: 140 patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women between 18-50 years old with desire of children and needs of embryo transfer.
• Plasma prolactin less than 30.
• Uterine cavity that allow pregnancy, body mass index between 20-30.
• And signed consent inform.

Exclusion criteria

• History of estrogen dependent cancer, unknown origin vaginal bleeding.
• Ovarian cyst.
• Contraindications to be pregnant.
• Estrogen allergy.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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140 participants in 2 patient groups

Oral strogen

Experimental group

Treatment:

Drug: Oral strogen

Transdermal strogen

Experimental group

Treatment:

Drug: Transdermal strogen