Endometrial Sampling (Pipelle)in IVF Patients

Sheba Medical Center

Status: Unknown

Conditions: Infertility

Treatments: Procedure: Pipelle (Endometrial Sampling)

Study type: Interventional

Funder types: Other

Identifiers

NCT00411021

SHEBA-05-3674-MB-CTIL

Details and patient eligibility

About

A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle. Seventy IVF patients will be randomly selected to undergo either endometrial biopsies or minimal cervical scratch on days 8-10 and 21-23 of their cycle, preceding the IVF treatment. If not pregnant, the women will continue for another IVF cycle, preceded by endometrial or cervical scratch complimentary to their procedure in the first cycle. The main major outcomes will include pregnancy rate, implantation rate, endometrial thickness, abortion rate, live births and embryo quality.

Sex: Female

Ages: 20 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Women undergoing IVF treatment
• Repeated Implantation failure

Exclusion criteria

• PID or suspected PID
• Undiagnosed Irregular Bleeding

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind