Endometriosis and ATR-FTIR Spectroscopy

Federal University of Espirito Santo

Status: Enrolling

Conditions: Endometriosis; Endometriomas

Treatments: Diagnostic Test: FTIR spectroscopy analysis

Study type: Interventional

Funder types: Other

Identifiers

NCT06426420

FTIR-ENDOMETRIOSIS

Details and patient eligibility

About

The goal of this study is to explore the use of mid-infrared spectroscopy (ATR-FTIR) as a detection tool for endometriosis in urine.

Full description

Endometriosis is a chronic gynecological disease that is considered debilitating and multifactorial. Its diagnosis is invasive and can be prolonged due to non-specific symptoms and erroneous or late investigations, which can lead to delays and impair the provision of adequate treatment.

ATR-FTIR Spectroscopy is a non-invasive technique with the capability to identify the chemical composition and molecular changes of samples through its interaction with mid-infrared radiation. The aim of this work is to develop a rapid test for the detection of endometriosis in urine samples using spectroscopy and machine learning algorithms.

Enrollment: 600 estimated patients

Sex: Female

Ages: 18 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Female
• Pelvic pain complain

Exclusion criteria

• Age under 18 or above 55
• Lack of informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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600 participants in 1 patient group

Pelvic Pain

Experimental group

Description:

Patients referred to the gynecology outpatient clinic, with complain of pelvic pain. Positives and negatives for endometriosis will be outlined by an expert gynecologist according to the following criteria: * Pelvic MRI (Magnetic Resonance Imaging) report; * Gynecologic exam; * Clinical symptoms and history; The intervention is the use of the ATR-FTIR Spectrometer in patient's urine samples to develop and validate a tool for detecting endometriosis.

Treatment:

Diagnostic Test: FTIR spectroscopy analysis