ENDOMETRIOSIS - MRI (ENDO-MRI)

University Hospital, Lille

Status: Enrolling

Conditions: Diagnosis; Endometriosis; Comparative Study; Pelvis; Mobility Limitation; Magnetic Resonance Imaging

Treatments: Other: Dynamic MRI Sequence

Study type: Observational

Funder types: Other

Identifiers

NCT05779462

2022-A02135-38 (Other Identifier)

2022_0032

Details and patient eligibility

About

Endometriosis is a frequent pathology with an estimated prevalence of 10% of women of childbearing age. There is no exact correspondence between the symptoms described by the patients and the severity of the lesions, which makes clinical diagnosis difficult. It therefore seems important to improve the complementary examinations available to make the diagnosis more precise and to better study the effectiveness of the treatments implemented. The clinical examination and per-surgical findings of patients with deep pelvic endometriosis show a clear decrease in the mobility of the pelvic organs in relation to each other, but few studies have looked at this mobility, which could however have an implication in explaining the pathophysiology of the disease and the symptomatology of the patients, as well as in the detection of lesions preoperatively. The persistence of hypo-mobility could also help to understand treatment failures.

Enrollment: 52 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient referred for suspected pelvic endometriosis requiring pelvic MRI
• Female, nulliparous,
• patient with signed written consent, patient with health insurance,
• patient willing to comply with all study procedures and duration

Exclusion criteria

• BMI > 35,
• history of hereditary collagen and elastic tissue disease,
• history of pelviperitonitis,
• history of major pelvic surgery,
• inability to receive informed information,
• inability to participate in the entire study,
• lack of social security coverage,
• refusal to sign consent

Trial design

52 participants in 2 patient groups

patients with pelvic endometriosis

Description:

Patients referred for suspected pelvic endometriosis, with pelvic endometriosis on initial MRI

Treatment:

Other: Dynamic MRI Sequence

patients without pelvic endometriosis

Description:

Patients referred for suspected pelvic endometriosis but without endometriosis found on diagnostic MRI.

Treatment:

Other: Dynamic MRI Sequence