Endoplasmic Reticulum Stress in Chronic Respiratory Diseases

Chonbuk National University

Status: Unknown

Conditions: ER Stress,; Lung Cancer,; Chronic Airway Disorders,; Interstitial Lung Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT01211015

RCPD ER stress

Details and patient eligibility

About

Aim: To investigate whether ER stress is implicated in the pathogenesis of various pulmonary disorders

Measurement:

1. Unfolded protein responses (UPRs) in blood (PBMCs)of patients

   1. CHOP
   2. GRP 78 and so on

2. Unfolded protein responses (UPRs) in blood (PBMCs)of healthy controls

   1. CHOP
   2. GRP 78 and so on

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• > 18 yrs
• Definitive diagnosis as chronic pulmonary diseases by physician

Exclusion criteria

• Any other chronic medical illness such as DM, HTN, and other malignancy

Trial design

50 participants in 2 patient groups

Control group

Description:

healthy control group

Disease group

Description:

asthma, COPD, ILD, lung malignancy