Endorectal Coil Magnetic Resonance Images (ERC-MRI)

University Health Network, Toronto

Status and phase

Completed

Phase 2

Conditions

Prostatic Neoplasms

Treatments

Procedure: Endorectal Coil Magnetic Resonance Images

Study type

Interventional

Funder types

Other

Industry

Identifiers

NCT00160953

UHN REB 05-0041-C

Details and patient eligibility

About

When we acquired MR images of the prostate gland using a coil (receiver antenna) inside the rectum, we can see areas with tumour in the prostate gland, and well as details of the anatomy. The coil inside the rectum changes the shape of the prostate gland. In order to use this images to help target radiation therapy to the tumour better, we need to deform the images to the original shape of the prostate gland without the coil. In this study, we will develop a way to deform the images accurately.

Sex

Male

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

adenocarcinoma of the prostate
patient undergoing dose escalated conformal EBRT
low or intermediate risk prognostic factors: PSA < or equa to20, gleason score <8, T <T3, N category 0 or X, M category 0 or X
> or equal to 18 years of age
ECOG performance status 0 or 1

Exclusion criteria

contraindications to MRI
bleeding diathesis and anti-coagulative therapy that cannot be temporarily ceased precluding insertion of fiducial markers
IFB or collagen vascular disease
previous colorectal surgery
previous pelvic RT