Endoscopic Evaluation After Esophagectomy

Nagasaki University

Status: Completed

Conditions: Constriction; Ischemia; Esophageal Neoplasms; Anastomotic Leak

Treatments: Procedure: Patients after esophagectomy

Study type: Observational

Funder types: Other

Identifiers

NCT02703142

NagasakiU

Details and patient eligibility

About

Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Full description

Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures. However the evaluation and prevention before developing gastric conduit ischemia have been established. The investigators have built a hypothesis that the evaluation for gastric mucosal ischemia in early phase after esophagectomy predict the complication of gastric conduit. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Enrollment: 10 patients

Sex: All

Ages: 20 to 84 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Malignant or end-stage benign esophageal disease.
• Esophagectomy with reconstruction by a gastric pull-up.

Exclusion criteria

• Severe heart failure and pulmonary dysfunction
• Severe renal and liver dysfunction
• Allergenic history
• Pregnancy

Trial design

10 participants in 1 patient group

Patients after esophagectomy

Description:

Endoscopic examinations are performed at 1, 8, and 15 postoperative days. Endoscopic examination is added when abnormal findings are demonstrated.

Treatment:

Procedure: Patients after esophagectomy