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Endoscopic Evaluation for Predicting the Complications Related to Gastric Conduit After Esophagectomy

N

Nagasaki University

Status

Completed

Conditions

Constriction
Ischemia
Esophageal Neoplasms
Anastomotic Leak

Treatments

Diagnostic Test: Patients after esophagectomy

Study type

Observational

Funder types

Other

Identifiers

NCT02937389
16082202

Details and patient eligibility

About

Gastric conduit ischemia or anastomotic breakdown after esophagectomy with cervical esophagogastrostomy often cause severe complications, such as leakage, necrotic organs, and strictures. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Full description

The development and improvement of thoracoscopic esophagectomy (TE) reduced the severe pulmonary complication after esophagectomy. However, the postoperative complications relative to gastric conduit reconstruction are still common issues after esophagectomy. The ischemia of the proximal portion of the graft predisposes these patients to a high incidence of anastomotic complications after esophagectomy. Less commonly, severe graft ischemia can lead to transmural necrosis. Thus, early diagnosis of ischemic reaction may provide the suitable postoperative management and therapeutic intervention to prevent leakage, strictures and necrosis. Thus, the purpose of this study is the safety and efficacy of endoscopic evaluation about reconstructive organs after esophagectomy. The investigators evaluate endoscopic predictions using classifications in acute phase after esophagogastrostomy.

Enrollment

60 patients

Sex

All

Ages

20 to 84 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Malignant or end-stage benign esophageal disease. Esophagectomy with reconstruction by a gastric pull-up.

Exclusion criteria

  • Severe heart failure and pulmonary dysfunction Severe renal and liver dysfunction Allergenic history Pregnancy

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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