Endoscopic Lung Volume Reduction Coil Treatment in Patients With Chronic Hypercapnic Respiratory Failure

Universitätsklinikum Hamburg-Eppendorf

Status: Terminated

Conditions: Emphysema

Treatments: Procedure: Endoscopic lung volume reduction coil treatment

Study type: Observational

Funder types: Other

Identifiers

NCT02996149

PV-5379

Details and patient eligibility

About

Endoscopic lung volume reduction coil treatment is a treatment option for selected patients with severe emphysema. In the advanced stages, emphysema may lead to chronic hypercapnic respiratory failure. In this observational study the safety and efficacy of endoscopic lung volume reduction coil treatment in patients with chronic hypercapnic respiratory failure is evaluated.

Enrollment: 1 patient

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with emphysema (chronic obstructive pulmonary disease with forced expired volume in one second (FEV1) < 50% predicted and residual volume (RV) ≥ 200% predicted) in whom endoscopic lung volume reduction coil treatment is performed
• Chronic hypercapnic respiratory failure (PaCO2 ≥ 50 mmHg)
• Informed consent

Exclusion criteria

• Therapeutic anticoagulation
• Anti-platelet therapy exceeding the use of acetylsalicylic acid
• Severe pulmonary hypertension