Endoscopic Scoring System Utilization in Inflammatory Bowel Disease

Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno

Status: Enrolling

Conditions: Inflammatory Bowel Diseases

Treatments: Procedure: colonoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT05576402

333

Details and patient eligibility

About

Inflammatory bowel diseases comprise two distinctive entities: Crohn's disease and ulcerative colitis. During the last decade, endoscopic assessment of inflammation has become relevant since it is a prognostic factor. As a consequence, therapeutic targets now contemplate mucosal healing as part of the goals to be achieved. Endoscopic scores for Crohn's disease and ulcerative colitis have been developed to objectively assess the mucosal inflammatory activity. Although they may have some limitations, these scores have been widely accepted in referral centers, especially since they have been adopted as standard evaluation in inflammatory bowel disease clinical trials . However, their use in the setting of endoscopic practice outside centers with a high volume or with less experience in clinical trials is not known.

Enrollment: 1,500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients who underwent colonoscopy for the evaluation of mucosal inflammatory activity
• Patients with an established diagnosis of either Crohn's disease or ulcerative colitis

Exclusion criteria

• Sigmoidoscopies performed in ulcerative colitis for the assessment of mucosal inflammatory activity