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Endoscopic Size Assessment of Advanced Adenomatous Polyps

Rush logo

Rush

Status

Completed

Conditions

Adenoma Detection Rate Improvement in Screening Colonoscopy

Study type

Observational

Funder types

Other

Identifiers

NCT02193646
ESA-2014

Details and patient eligibility

About

The investigators are retrospectively comparing detection rates of adenomatous polyps, advanced adenomas, and size assessment of the polyps among Rush University Medical Center endoscopists. The investigators plan to review whether the size assessment of adenomatous polyps affected the surveillance protocols and if the location of polyps detected affected the detection rates.

Full description

The study plans to compare detection rates of adenomatous as well as the sessile serrated polyps, advanced adenomas and size assessment of the polyps among the endoscopists at the study site. In addition, the study team aims to evaluate rates of advanced neoplasia on surveillance colonoscopy based on certain features on initial colonoscopy and patient characteristics, including specific high-risk histologic features and concurrent medication usage such as aspirin. In addition, patients with at least one adenoma on surveillance colonoscopy will be identified and regarded as cases. Cases will be compared against normal surveillance colonoscopy. The Controls will be selected on a 1:1 ratio. Aspirin use will be compared between groups.

Enrollment

1,930 patients

Sex

All

Ages

40 to 80 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Presence of adenomatous polyps detected at endoscopy and diagnosed pathologically by tissue biopsy
  • Have a colonoscopy at RUMC for screening purposes

Exclusion criteria

  • Failure to meet inclusion criteria
  • Previous diagnosis of IBD or colorectal cancer

Trial contacts and locations

1

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Central trial contact

Amanda Lin; GI Research

Data sourced from clinicaltrials.gov

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