Endoscopic Transcanal Tympanoplasty With Attico-antrostomy Versus Endoscopic-assisted Canal Wall up Mastoidectomy in Management of Localized Cholesteatoma: A Randomized Clinical Trial

Mansoura University

Status: Completed

Conditions: Cholesteatoma

Treatments: Procedure: endoscopic assisted canal wall up mastoidectomy; Procedure: endoscopic transcanal tympanoplasty with attico-antrostomy

Study type: Interventional

Funder types: Other

Identifiers

NCT04959539

MS/17.05.161

Details and patient eligibility

About

the main objective of the study is to compare endoscopic transcanal tympanoplasty with attico-antrostomy with endoscopic assisted canal wall up mastoidectomy in treatment of limited attic cholesteatoma.

Enrollment: 40 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Cases of cholesteatoma limited to the middle ear and/or attic but not extending beyond the posterior end of the lateral semicircular canal (LSCC) proved radiologically with computed tomography (CT) scan

Exclusion criteria

• Cases in which cholesteatoma extended beyond the attic were excluded as being potentially beyond the limits of the TEES approach

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

endoscopic transcanal tympanoplasty with attico-antrostomy

Active Comparator group

Treatment:

Procedure: endoscopic transcanal tympanoplasty with attico-antrostomy

endoscopic assisted canal wall up mastoidectomy

Active Comparator group

Treatment:

Procedure: endoscopic assisted canal wall up mastoidectomy