Endoscopic Ultrasound (EUS) Guided Fine Needle Aspiration (FNA) EUS-FNA of Solid Pancreatic Mass Lesions Using a Novel Corkscrew Technique: a Pilot Study

Johns Hopkins University

Status

Terminated

Conditions

Pancreatic Cancer

Treatments

Procedure: EUS-FNA with Corkscrew technique

Device: Expect 19 G Flex needle

Study type

Interventional

Funder types

Other

Identifiers

NCT02116322

NA_00090101

Details and patient eligibility

About

This research is being done to investigate if a new technique to biopsy the pancreas will lead to a larger amount tissue material that can be analyzed. Investigators have called the technique the "corkscrew" technique and believe it will allow obtaining a larger biopsy sample during the endoscopic ultrasound examination. The corkscrew technique uses a clockwise rotational movement to drive the needle into the pancreatic mass (like a wine bottle opener twists and buries itself into a cork). It is believed that this will lead to a better biopsy sample than the usual way and therefore result in a higher chance of a diagnosis.

Enrollment

4 patients

Sex

All

Ages

18 to 90 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

In-patients and out-patients between the age of 18 and 90 years with solid pancreatic masses presenting for EUS-Fine Needle Aspiration (FNTA)

Exclusion criteria

Uncorrectable coagulopathy (INR > 1.5)
Uncorrectable thrombocytopenia (platelet < 50,000)
Uncooperative patients
Pregnant women (women of childbearing age will undergo urine pregnancy testing, which is routine for all endoscopic procedures)
Refusal to consent form
Prior negative FNTA
In situ metallic biliary stents
Predominantly cystic lesions
Inaccessible lesions to EUS