Endoscopic Ultrasound Evaluation of the Common Bile Duct in Patients With Obstructive Jaundice Due to Bilio-pancreatic Malignancies (ECCO Trial)

Ramsay Générale de Santé

Status: Completed

Conditions: Bilio-pancreatic Tumor; Obstructive Jaundice

Treatments: Procedure: Ultrasound endoscopy

Study type: Observational

Funder types: Other

Identifiers

NCT05155475

2018-A03461-54

Details and patient eligibility

About

To assess the size of the common bile duct in a large cohort of patients with jaundice following a malignant tumor of the head of the pancreas or the distal bile duct receiving a diagnostic EA for biopsy and / or for evaluation of tissue resectability.

Enrollment: 20 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with jaundice and an injury to the head of the pancreas recommended for EUS-guided tissue acquisition or staging
• Patients with jaundice and distal CBD lesion suggestive of cholangiocarcinoma or Vater's ampulla carcinoma recommended for EUS-guided tissue acquisition or staging
• Serum bilirubin level ≥ 3 mg / dl
• Age ≥ 18 years old
• Subject affiliated or beneficiary of a social security scheme.
• Subject having been informed of this study and having given his no objection

Exclusion criteria

• Presence of altered anatomy due to previous gastric surgery (Billroth II or Roux-en-Y anastomosis)
• Sphincterotomy performed previously, plastic biliary stent or metal stent placement
• Percutaneous drainage of the bile ducts performed previously
• Pregnant, breastfeeding or parturient woman
• Protected patients: Adults under guardianship, curatorship or other legal protection, deprived of their liberty by judicial or administrative decision; hospitalized without consent.

Trial design

20 participants in 1 patient group

Patient with jaundice

Treatment:

Procedure: Ultrasound endoscopy