Endoscopic Ultrasound-guided Needle-based Confocal Laser Endomicroscopy in Solid Pancreatic Masses

Shandong University

Status: Unknown

Conditions: Solid Pancreatic Masses

Study type: Observational

Funder types: Other

Identifiers

NCT02936960

2016SDU-QILU-20

Details and patient eligibility

About

The differential diagnosis of solid pancreatic masses by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) is currently suboptimal. Needle-based confocal laser endomicroscopy (nCLE) is a novel endoscopic technique, which is compatible with the 19-gauge FNA needle. Under endoscopic ultrasonography (EUS) guidance, nCLE enables real-time in vivo imaging of lesion tissues at cellular and subcellular levels. This study aimed to describe nCLE interpretation criteria for the characterization of pancreatic masses, with histopathological correlation, and to perform the validation of these criteria.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with any pancreatic mass

Exclusion criteria

• Patients aged <18 years or >80 years
• Known allergy to fluorescein dye
• Previous EUS-FNA performed within the past 3 months, and usualcontraindications to EUS-FNA
• Pregnancy or breastfeeding
• Inability to provide informed consent