Endoscopic Versus Open Lumbar Discectomy in Diabetic Patients

Al-Azhar University

Status: Enrolling

Conditions: Diabetes Mellitus; Endoscope; Open; Lumbar Discectomy

Treatments: Procedure: Open lumbar discectomy; Procedure: Endoscopic lumbar discectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT07060846

DFM-IRB 00012367-25-06-009

Details and patient eligibility

About

This study aims to compare the endoscopic versus open lumbar discectomy in diabetic patients.

Full description

Diabetes mellitus (DM) is a highly prevalent disease with the capacity to adversely affect nearly every major organ system. DM has been demonstrated as a risk factor for a variety of complications within medical and surgical spheres Open lumbar discectomy is the most common surgical discectomy technique and is considered by many to be the gold standard.

Endoscopic lumbar discectomy allowed spinal surgeons to decompress a symptomatic lumbar nerve root by using an endoscopic minimally invasive surgical approach.

Enrollment: 50 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age from 18 to 75 years.
• Both sexes.
• Patients suffering from prolapsed lumbar disc postero-lateral, single level disc herniation at L4-5 or L5-S1 level with low back pain and unilateral radiculopathy and failure of conservative treatment for 12 weeks

Exclusion criteria

• Extraforaminal disc herniation.
• Recurrent and/or multiple level discs prolapses.
• Spondylolisthesis.
• Prior lumbar surgery at the same spinal level.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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50 participants in 2 patient groups

Group I

Experimental group

Description:

Patients will undergo endoscopic lumbar discectomy.

Treatment:

Procedure: Endoscopic lumbar discectomy

Group II

Active Comparator group

Description:

Patients will undergo an open lumbar discectomy.

Treatment:

Procedure: Open lumbar discectomy