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Endothelial Dysfunction Induced by Postprandial Lipemia

N

Norwegian University of Science and Technology

Status and phase

Completed
Phase 2

Conditions

Healthy Subjects

Treatments

Other: exercise training

Study type

Interventional

Funder types

Other

Identifiers

NCT00660491
Exercise, Food and Endothelium

Details and patient eligibility

About

Postprandial lipemia and exercise oppose each other in terms of cardiovascular risk, however the mechanism of their interaction is not well understood.

Therefore we want to study vascular function, as assessed by brachial artery (BA) flow mediated dilation (FMD), in healthy men before and after a high fat meal (HFM) preceded (16-18 hrs) by rest, a single bout of continuous moderate intensity exercise (CME), and high intensity interval exercise (HIIE).

Enrollment

8 patients

Sex

Male

Ages

20 to 40 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • male, 20-40years, BMI between 25 and 30, resident in Trondheim.

Exclusion criteria

  • unstable angina, CHD, heart failure,

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Crossover Assignment

Masking

Double Blind

8 participants in 3 patient groups

1
No Intervention group
Description:
Control
2
No Intervention group
Description:
moderate exercise training group
3
Experimental group
Description:
high intensity exercise group
Treatment:
Other: exercise training

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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