Endotracheal Intubation Without Muscle Relaxants

Majadahonda Iron Gate University

Status

Completed

Conditions

Intubation Complication

Muscle Relaxation

Treatments

Drug: Sevoflurane 8% + Intravenous fentanyl

Other: Avoidance of rocuronium/cisatracurium

Study type

Interventional

Funder types

Other

Identifiers

NCT03112564

HUPH:PI:13/15

Details and patient eligibility

About

Prospective study conducted between March 2013 and November 2014 at Hospital Universitario Puerta de Hierro-Majadahonda, in Madrid, Spain to identify complications and evaluate the efficacy of pure inhalational anesthesia induction to achieve endotracheal intubation without the use of muscle relaxant and analgesic drugs.

Full description

This is a prospective study conducted between March 2013 and November 2014 at Hospital Universitario Puerta de Hierro-Majadahonda, in Madrid, Spain, with the previous approval by the institutional clinical research ethics committee. A total of 91 subjects who underwent general, gastrointestinal, orthopedic, urology and neurological surgery were randomly selected and provided written informed consent before any study-related procedures were performed.

The aim of this study was to identify complications and evaluate the efficacy of pure inhalational anesthesia induction to achieve endotracheal intubation without the use of muscle relaxant and analgesic drugs.

Enrollment

91 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male or Female patients
Age ≥ 18 years
ASA ≤ 3
Able to provide informed consent

Exclusion criteria

Subjects with left ventricle ejection fraction (LEVF) ≤ 35%
History of ischemic heart disease in the last year
History of malignant hyperthermia
Presence of thoracic drain tubes
Increased intracranial pressure (ICP) or brain tumors, undergoing neurophysiological monitoring
Hemodynamic instability or likely to become unstable during induction of anesthesia