Endovascular Denervation in Patients With Cancer Pain

Southeast University

Status

Unknown

Conditions

Cancer Pain

Treatments

Device: endovascular denervation

Study type

Interventional

Funder types

Other

Identifiers

NCT03431922

ED treatment

Details and patient eligibility

About

Endovascular arterial denervation (ED) is a minimally invasive technique which could reduce the occurrence of injury of visceral tissue or organs. As the principle of renal denervation (RDN), Radiofrequency energy delivered by a multi-electrode catheter to the celiac plexus over the anterolateral surface of the superior mesenteric artery (SMA) and the celiac axis. Damaged or partially damaged celiac plexus can achieve the effect of pain relief.

Full description

The multi-electrode catheter was consisted of six independent electrodes helically on a net structure, which could be set as the same energy and temperature for simultaneous multi-point ablation. A real-time monitoring capability also provided by the display.

Enrollment

20 estimated patients

Sex

All

Ages

25 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

25 to 75 years
severe cancer pain with the visual analogue scores of no less than 7

Exclusion criteria

pregnant or intent to become pregnant within 1 year
postural hypotension
uncorrected coagulation dysfunction
aortic aneurysm or dissection
type 1 diabetes mellitus (T1DM)
acute or severe systemic infection
history of cerebral apoplexy or transient ischemic attack (TIA) in the past two weeks
history of acute coronary syndrome in the past two weeks
participants who are not suitable to be enrolled into the study assessed by the researchers