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The investigators compare different endovascular techniques as an alternative to surgical reconstruction to repair JAAS regarding ; success rates, 30-day mortality,endoleak events secondary intervention rates
Full description
Aortic disease is the direct cause of close to 10000 deaths annually in the United States. 1
Aneurysmal disease can affect any segment of the aorta, from the aortic root to the aortic bifurcation. Juxtarenal Aortic Aneurysms (JAA) (where a specialty designed custom -made device (endograft)which has holes, or fenestrations ,on the graft body to maintain the patency of the visceral arteries) account for approximately 15% of abdominal aortic aneurysms.2
Successful aortic aneurysm treatment depends on either open replacement or endovascular exclusion of the aneurysmal segment with healthy artery proximal and distal to the repair.
The decision to treat an AAA is based on the associated risk of treatment, the risk of aneurysm rupture, the patient's life expectancy, and patient preference.
The primary determinant of rupture risk is maximum aneurysm diameter, with negligible rupture risk in aneurysms <4cm in diameter compared with aneurysms >8 cm . 3, 4.
The Society for Vascular Surgery recommends repair for all patients of acceptable perioperative risk with an AAA ≥5.5 cm in diameter as well as all patients with saccular and symptomatic aneurysms.5 ,6
These guidelines also suggest repair for women at a diameter of 5.0 cm.
Fenestrated Endovascular Aneurysm Repair (FEVAR) and Chimney Endovascular Aneurysm Repair (CHEVAR)are both effective methods to treat JAAs
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Inclusion criteria
• Subject is ≥18 years old
Exclusion criteria
Subject is participating in a concurrent study which may confound study results
Subject has a life expectancy ≤1 year
Subject has an aneurysm that is:
Subject requires emergent aneurysm treatment, for example, trauma or rupture
Subject has previously undergone surgical treatment for abdominal aortic aneurysm
Subject is a female of childbearing potential in whom pregnancy cannot be excluded
Subject has a known hypersensitivity or contraindication to anticoagulants, anti-platelets, or contrast media, which is not amenable to pre-treatment.
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Interventional model
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30 participants in 1 patient group
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Central trial contact
Ashraf M Abo Bakr, MD; Khaled M Awad, Master
Data sourced from clinicaltrials.gov
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