Endtidal Carbon Dioxide for Earlier Detection of Pulmonary Hypertension (EARLIER)

University of Giessen

Status: Invitation-only

Conditions: Hypertension, Pulmonary; Lung Diseases; Chronic Thromboembolic Pulmonary Hypertension; Vascular Diseases; Hypertension;Pulmonary;Primary

Treatments: Diagnostic Test: Capnography

Study type: Observational

Funder types: Other

Identifiers

NCT03388476

AZ 156/17 (Other Identifier)

DRKS00013589 (Registry Identifier)

Details and patient eligibility

About

Measurement of the endtidal carbon dioxide by capnography to exclude or to ensure the diagnosis pulmonary hypertension. The aim of the study is to obtain an endtidal carbon dioxide cut-off value for the diagnostic algorithm for pulmonary hypertension as an easily measurable and cheap diagnostic tool in patients with suspicion of pulmonary hypertension.

Full description

The disease pulmonary hypertension is due to a remodeling of the lung vessels which results in a change of the exhaled air. This change is measurable with a so called capnograph. The investigators want to measure the breath from patients with and without pulmonary hypertension to detect a cut-off value for the diagnosis pulmonary hypertension.

Patients which have the probably diagnosis pulmonary hypertension and are older than 18 years are investigated. This patients will get an right heart catheterization and a measurement from their exhaled air.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

Age > 18 years, suspicion of pulmonary hypertension, planned or accomplished right heart catheterization

Exclusion criteria

none

Trial design

500 participants in 1 patient group

Suspicion of pulmonary hypertension

Description:

At Patients with suspicion of pulmonary hypertension, which get a right heart catheterization, in the context of the study the exhaled air, precious the endtidal carbon dioxide (CO2), before or after the right heart catheterization will be measured through capnography.

Treatment:

Diagnostic Test: Capnography