Energy Turnover and Appetite (NEXT)

University Hospital, Clermont-Ferrand

Status: Enrolling

Conditions: Obesity

Treatments: Behavioral: Low energy turnover

Study type: Interventional

Funder types: Other

Identifiers

NCT05365685

RBHP 2021 BOIRIE 2

2021-A02867-34 (Other Identifier)

Details and patient eligibility

About

The aim of the study is to compare the effect of a low versus moderate versus high energy turnover on energy intake, appetite and food reward, in adolescents with obesity. 18 adolescents with obesity will then complete three experimental sessions in a randomized order: low, high and moderate Energy turnover.

Full description

A total of 18 adolescents with obesity, aged 12-16 years olds will complete three experimental sessions in a randomized order: i) low energy turnover; ii) Moderate energy turnover and ; iii) High energy turnover. Their ad libitum energy intake at dinner will be assessed through an ad libitum buffet-type meal, their food reward assessed right before the dinner meal and their appetite sensation at regular intervals during the day.

Enrollment: 18 estimated patients

Sex: All

Ages: 12 to 16 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• BMI percentile > 97th percentile according to the french curves.
• ages 12-16 years old
• Signed consent form
• being registered in the national social security system
• no contraindication to physical activity

Exclusion criteria

Previous surgical interventions that is considered as non-compatible with the study.

• Diabetes
• weight loss during the last 6 months
• cardiovascular disease or risks

Trial design

Primary purpose: Basic Science

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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18 participants in 1 patient group

adolescents with obesity

Experimental group

Description:

There is only one arm as this is an acute randomized study comparing three different conditions within the same sample of participants.

Treatment:

Behavioral: Low energy turnover