Energy Value of Lentils and Chickpeas

Beltsville Human Nutrition Research Center (BHNRC)

Status: Completed

Conditions: Healthy Adults

Treatments: Other: Lentil Containing Diet; Other: Chickpea Containing Diet; Other: Control Diet

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT03779971

HS66-Lentil/Chickpea Study

Details and patient eligibility

About

This study is being conducted to determine the digestibility of and available energy from pulses.

Full description

Previous studies have demonstrated that the metabolizable energy (energy available to the body) from tree nuts is less than predicted by the Atwater factors (the standard approach to determining calorie value of a food). The Atwater approach is over 100 years old and is inaccurate for some foods. This study will be conducted to determine the metabolizable energy from two pulses, lentils and chickpeas. The study will be a human nutrition intervention involving consumption of a controlled diet followed by collection of urine and feces.

Enrollment: 18 patients

Sex: All

Ages: 25 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• BMI between 19 and 38 kg/m2
• Age 25 to 75 years during intervention

Exclusion criteria

• Known (self-reported) allergy or adverse reaction to study foods
• Women who have given birth during the previous 12 months or who are pregnant/lactating or who plan to become pregnant during the study
• History of bariatric surgery or nutrient malabsorption disease (such as celiac disease), Crohn's disease, diabetes, or metabolic disorders that may interfere with the study
• History of certain cancer diagnosis or treatment in the last 3 years
• Smoking or use of tobacco products in the past 6 months
• Suspected or known strictures, fistulas or physiological/mechanical GI obstruction
• Use of certain medications or supplements (prescription or over-the-counter) that may interfere with the study objectives, including blood thinning medications
• Unable or unwilling to give informed consent or communicate with study staff
• Self-report of alcohol or substance abuse within the past 12 months and/or current treatment for these problems (long-term participation in Alcoholics Anonymous is not an exclusion)
• Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Double Blind

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18 participants in 3 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

The placebo comparator will be a fully controlled diet made from typical American foods and containing no beans or pulses.

Treatment:

Other: Control Diet

Lentil

Experimental group

Description:

The lentil arm will consist of a fully controlled diet made from the same foods as the placebo arm and will also contain lentils.

Treatment:

Other: Lentil Containing Diet

Chickpeas

Experimental group

Description:

The chickpea arm will consist of a fully controlled diet made from the same foods as the placebo arm and will also contain chickpeas.

Treatment:

Other: Chickpea Containing Diet