Enhanced Prediction Model for Major Adverse Events Following Acute Myocardial Infarction

Zhejiang University

Status: Not yet enrolling

Conditions: Myocardial Infarction (MI)

Treatments: Procedure: Percutaneous coronary intervention

Study type: Observational

Funder types: Other

Identifiers

NCT07250152

2025-1224

Details and patient eligibility

About

Acute myocardial infarction (AMI) remains a leading cause of mortality worldwide. Although early revascularization has markedly improved short-term outcomes, the incidence of major adverse cardiovascular events after the index event remains unacceptably high, posing a formidable clinical challenge. Contemporary risk-stratification instruments rely predominantly on a restricted set of conventional clinical variables and therefore fail to capture the full spectrum of individual pathophysiological complexity. To overcome these limitations, the present investigation aims to develop a post-AMI prognostic model that integrates comprehensive multimodal data.

Enrollment: 1,544 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Age ≥18 years old
2. Presented with myocardial infarction, including NSTEMI and STEMI
3. Undergoing successful percutaneous coronary intervention.

Exclusion criteria

1. Subjects who decline protocol-mandated follow-up or withhold informed consent.
2. Individuals whose expected survival is < 1 year.

Trial design

1,544 participants in 1 patient group

MI group

Description:

Patients who present with myocardial infarction and undergo successful percutaneous coronary intervention will be eligible for enrollment.

Treatment:

Procedure: Percutaneous coronary intervention