Enhanced Recovery After Surgery in Extremity Sarcoma

Joshua Lawrenz

Status: Enrolling

Conditions: Sarcoma

Treatments: Procedure: Enhanced Recovery After Surgery

Study type: Interventional

Funder types: Other

Identifiers

NCT04461171

VICC SAR 2020

Details and patient eligibility

About

The purpose of this study is to demonstrate the efficacy of implementing the enhanced recovery after surgery (ERAS) pathway in a prospective manner to patients undergoing surgical treatment for extremity sarcoma.

Full description

Specifically, the focus of this study will be regarding the administration of a perioperative non-narcotic, multimodal pain management pathway. Primary endpoints collected with be short-term patient reported outcomes (pain scores [PROMIS] and [QoR-15]), limb function scores [MSTS], and key clinical outcomes (hospital length of stay, opioid requirements/prescribing data and perioperative complications).

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Any patient at Vanderbilt University Medical Center treated with surgical excision of a suspected extremity sarcoma
• Adult patients >17 years of age
• Patients of all preoperative opioid status (naïve or dependent)

Exclusion criteria

• Patients treated non-operatively
• Non-English speaking patients

Trial design

Primary purpose: Treatment

Allocation: Non-Randomized

Interventional model: Sequential Assignment

Masking: None (Open label)

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120 participants in 2 patient groups

ERAS

Experimental group

Description:

Administration of a perioperative non-narcotic, multimodal pain management pathway.

Treatment:

Procedure: Enhanced Recovery After Surgery

Non-ERAS (Conventional)

No Intervention group

Description:

Administration of a conventional perioperative pain management pathway that consists of both narcotic and non-narcotic pain medications.