Enhanced Recovery After Uvulopalatoplasty

Zagazig University

Status: Not yet enrolling

Conditions: Analgesia; Recovery, Psychological

Treatments: Procedure: Glossopharyngeal nerve block; Other: Standard multimodal analgesia

Study type: Interventional

Funder types: Other

Identifiers

NCT07246694

Uvulopalatoplasty Analgesia

Details and patient eligibility

About

Obstructive sleep apnea is a prevalent condition often treated surgically with palatoplasty, which improves airway patency and reduces apneic events. However, postoperative pain and airway discomfort following palatoplasty can be significant, leading to delayed oral intake, increased opioid consumption, and prolonged recovery. Combining an ultrasound-guided glossopharyngeal nerve block with topical airway anesthesia may provide synergistic analgesia and support a safer recovery profile.

Full description

Obstructive sleep apnea is a prevalent condition often treated surgically with palatoplasty, which improves airway patency and reduces apneic events. However, postoperative pain and airway discomfort following palatoplasty can be significant, leading to delayed oral intake, increased opioid consumption, and prolonged recovery. Enhanced Recovery After Surgery protocols aim to accelerate functional recovery and reduce perioperative morbidity. Combining an ultrasound-guided glossopharyngeal nerve block with topical airway anesthesia may provide effective analgesia and support a smoother recovery profile.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Confirmed diagnosis of moderate to severe obstructive sleep apnea.
• Patients scheduled for elective palatoplasty under general anesthesia.
• American Society of Anesthesiologists Physical Status class I and II.

Exclusion criteria

• Patients with chronic opioid use.
• Advanced hepatic, renal, cardiovascular, and neurologic diseases.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

Group I

Active Comparator group

Description:

The patient will receive the ultrasound-guided glossopharyngeal nerve block combined with topical airway anesthesia.

Treatment:

Procedure: Glossopharyngeal nerve block

Group c

Active Comparator group

Description:

The patient will receive the standard multimodal analgesia.

Treatment:

Other: Standard multimodal analgesia