Enhanced Recovery Program After Laparoscopic Colon Cancer Surgery

Kyungpook National University

Status: Terminated

Conditions: Colon Cancer

Treatments: Other: Enhanced recovery program

Study type: Interventional

Funder types: Other

Identifiers

NCT02399631

KNUHCRC005

Details and patient eligibility

About

An enhanced recovery program has been developed to provide for colon cancer patients faster and more personalized postoperative treatment. Most of the previous studies have showed that the efficacy of the enhanced recovery program on both subjective and objective physical recovery of patients. However, such studies are rarely conducted in South Korea. The purpose of this study is to evaluate the feasibility and efficacy of a postoperative enhanced recovery program in patients who underwent laparoscopic colon cancer surgery at a tertiary hospital in Korea.

Enrollment: 180 patients

Sex: All

Ages: 20 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Eligibility rule of enrollment
• ECOG 0-2
• Pathologically diagnosed colon cancer
• Stage I-III
• No functional disturbance in liver, kidney, bone marrow
• Informed consent

Exclusion criteria

• Emergent operation
• Obstructive or perforated cancer
• Rectosigmoid or rectal cancer
• Synchronous tumor
• Uncontrolled psychiatric or neurologic problems
• Severe hepatic dysfunction (GOT, GPT ≥100IU/L)
• Renal dysfunction (Cr ≥2mg/dl)
• Recent MI, CVA, nitrate medication

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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180 participants in 2 patient groups

ERAS group

Experimental group

Description:

early recovery program with no preoperative mechanical bowel preparation, early diet initiation, and prevention of postoperative ileus after elective laparoscopic colon cancer surgery

Treatment:

Other: Enhanced recovery program

Congrol group

No Intervention group

Description:

Traditional, conventional perioperative treatment