Enhanced Triage for COVID-19 (ETC-19)

University Health Network, Toronto

Status: Completed

Conditions: COVID-19; SARS-CoV 2

Study type: Observational

Funder types: Other

Identifiers

NCT04750369

20-5225

Details and patient eligibility

About

This study is to evaluate of the accuracy of biomarkers (i.e. circulating endothelial and immune activation markers) that indicate progression to severe disease in patients with suspected COVID-19 in the Emergency Department. It is a prospective observational study of patients presenting to emergency departments with a clinical suspicion of COVID19. All participants will have plasma samples collected for biomarker analysis, and will be tested for SARS-CoV-2 infection with a nasopharyngeal swab. Participants will be managed according to the best local practices.

Enrollment: 806 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients presenting with clinical suspicion of COVID-19 infection, as per UHN case definition at the time of presentation
• Age >18 years
• Ability to provide verbal informed consent

Exclusion criteria

• Patients who are not suspected of COVID-19 infection, as per UHN definition at the time of presentation