Enhancement of Postocclusive Reactive Hyperaemia by Dipyridamole

Radboud University Medical Center

Status: Completed

Conditions: Hypoxia; Hyperemia

Treatments: Drug: dipyridamole; Drug: caffeine

Study type: Interventional

Funder types: Other

Identifiers

NCT00268554

PORH-dipy

Details and patient eligibility

About

The purpose of this study is to determine whether dipyridamole enhances postocclusive reactive hyperaemia by increasing extracellular adenosine concentrations during ischemia and reperfusion. Furthermore we hypothesize that dipyridamole augments postocclusive reactive hyperaemia by increasing adenosine receptor stimulation.

Enrollment: 12 estimated patients

Sex: All

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy volunteers between 18 and 50 years

Exclusion criteria

• none specified

Trial design

Primary purpose: Basic Science

Allocation: Non-Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)