Enhancing Antiepileptic Drug Adherence

Qazvin University Of Medical Sciences

Status: Completed

Conditions: Epilepsy

Treatments: Behavioral: Routine counseling; Behavioral: Motivational Interviewing (MI)

Study type: Interventional

Funder types: Other

Identifiers

NCT02165306

214588

Details and patient eligibility

About

More than half of patients with epilepsy achieve full control of their seizures with antiepileptic drugs (AEDs).The study is aimed to investigate effectiveness of an educational intervention in improving medication adherence in patients with epilepsy.

Enrollment: 280 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of epilepsy according to the International League Against Epilepsy criteria
• age equal or higher than 18 years
• independence in daily living activities
• absence of major cognitive impairment or active psychiatric disorders

Exclusion criteria

• presence of a rapidly progressing neurological or medical disorder
• patients not receiving anti-epileptic drugs
• a history of significant substance abuse within the past year
• a diagnosis of mental retardation

Trial design

Primary purpose: Health Services Research

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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280 participants in 2 patient groups

Intervention

Experimental group

Description:

Patients enrolled in the intervention arm will receive two educational sessions on the importance of medication and barriers to adherence

Treatment:

Behavioral: Motivational Interviewing (MI)

Active Comparator

Active Comparator group

Description:

Usual Care The usual care group received routine counseling performed by the neurologist/neurosurgeon and nurses.

Treatment:

Behavioral: Routine counseling