Enhancing Hair Density With Platelet Rich Fibrin Matrix (PRFM)

The New York Eye & Ear Infirmary

Status and phase: Completed; Phase 3

Conditions: Alopecia

Treatments: Biological: PRFM treatment

Study type: Interventional

Funder types: Other

Identifiers

NCT01590238

2012-1

Details and patient eligibility

About

Clinical alopecia occurs due to miniaturization of the hair shafts as well as loss of active production of hair shafts. PRFM has been shown to induce dermal angiogenesis, and anecdotal findings of improvement of hair appearance after PRFM injection in the scalp suggest that PRFM may play a role in the treatment of thinning hair. Patients will be treated on a monthly basis with intradermal injections of autologous PRFM for 3 months. Changes in hair density will be assessed by comparing pre- and post-treatment photographs and non-invasive measurements of hair density at 1, 2, 3, 4 and 6 months after initial treatment.

Enrollment: 15 patients

Sex: All

Ages: 18 to 75 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• age 18- 75 years old
• frontal and/or crown alopecia

Exclusion criteria

• bleeding disorder

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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15 participants in 1 patient group

Treatment with PRFM

Experimental group

Description:

Subjects treated monthly 3 times with intradermal injections of PRFM into bald/balding scalp. Post-treatment hair density index measured and compared to hair density index measured prior to treatment for each subject.

Treatment:

Biological: PRFM treatment