Entamoeba Gingivalis and Periodontal Disease

Cairo University (CU)

Status

Completed

Conditions

Periodontal Diseases

Treatments

Other: Plaque Samples

Study type

Observational

Funder types

Other

Identifiers

NCT03805724

15062006

Details and patient eligibility

About

This current study aims to clarify the relationship between the occurrence of Entamoeba gingivalis infection and the specter of gingivitis & chronic periodontitis among Egyptian patients in comparison to healthy volunteers as a control group.

Full description

Three groups will be included in the current study. 40 Plaque samples will be collected from gingivitis patients (group 1), 40 from chronic periodontitis patients (group 2) plus 40 samples from healthy volunteers (group 3). Diagnosis of parasitic stages will rely on direct microscopic detection using permanent stains, Trichrome stain and haematoxylin and eosin stain in addition to direct wet mount examination.

Enrollment

120 patients

Sex

All

Ages

35 to 55 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Chronic Gingivitis patients with signs of clinical inflammation with no clinical attachment loss.
Chronic Periodontitis patients having probing depth of ≥3 mm and clinical attachment level ≥ 1 mm.
The control group: healthy subjects who attend the restorative dental clinic and had clinically healthy gingiva.

Exclusion criteria

Patients with any systemic diseases

Trial design

120 participants in 3 patient groups

Periodontally healthy subjects

Description:

They will be selected from healthy subjects who attend the restorative dental clinic and has clinically healthy gingiva with zero plaque index, gingival index and clinical attachment level \& probing depth ≤ 3 mm. Plaque samples will be collected.

Treatment:

Other: Plaque Samples

Chronic Periodontitis

Description:

Chronic periodontitis patients having probing depth of ≥3 mm and clinical attachment level ≥ 1 mm. Plaque samples will be collected.

Treatment:

Other: Plaque Samples

Chronic Gingivitis

Description:

Gingivitis patients having signs of clinical inflammation with no clinical attachment loss. Plaque samples will be collected

Treatment:

Other: Plaque Samples