Environmental Treatment for Seasonal Affective Disorder (SAD)

Yale University

Status: Completed

Conditions: Seasonal Affective Disorder

Treatments: Device: Inactivated negative ion generator; Device: Litebook treatment devices

Study type: Interventional

Funder types: Other

Identifiers

NCT00139997

22,777 (Other Identifier)

Details and patient eligibility

About

The purpose is to study treatments of Seasonal Affective Disorder (SAD).

Full description

This is a multicenter, randomized controlled trial of negative ion generation versus light-emitting diode phototherapy for seasonal affective disorder. Participants appropriate for the study are subjects with a DSM IV diagnosis of Major Depression, with seasonal pattern, winter type. Subjects were seen at Yale University,New Haven,CT University of British Columbia,Vancouver,BC Groningen University Hospital,Groningen, The Netherlands, Royal Ottawa Hospital, Ottawa,Ontario, McGill University, Montreal,Quebec, University Hospital,Saskatoon, Saskatchewan. The trial is 4 weeks in duration.

This trial has now been completed.

Enrollment: 26 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects meet DSM-IV criteria for major depressive episodes with a seasonal pattern, winter type.

Exclusion criteria

• Significant suicidal risk
• Serious medical illness
• Pregnancy
• Other DSM-IV diagnoses
• Taking mood altering medication
• May not travel to a sunny destination during study

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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26 participants in 2 patient groups, including a placebo group

LED phototherapy device

Experimental group

Description:

Litebook treatment devices: LED phototherapy device, used for 30 min before 8 am

Treatment:

Device: Litebook treatment devices

Inactivated Negative Ion Generator

Placebo Comparator group

Description:

Equivalent exposure to inactivated negative ion generator

Treatment:

Device: Inactivated negative ion generator