Epidemiological Characteristics and Treatment Protocol for Carbapenem-Resistant Klebsiella Pneumoniae in China

Zhejiang University

Status: Unknown

Conditions: Klebsiella Pneumoniae Infection

Treatments: Other: Carbapenem-Resistant Klebsiella pneumoniae

Study type: Observational

Funder types: Other

Identifiers

NCT03245632

SRRSH-CRKP

Details and patient eligibility

About

Klebsiella pneumoniae is one of the most common pathogens causing nosocomial infection. Recently, the emergency of Carbapenem-Resistant Klebsiella pneumoniae (CRKP) had cause the clinical therapy be very difficult. However, there is not much empirical data as to the prevalence, risk factors, characteristics, and the rationality of the current therapy for the CRKP infection. Thus, the study was aimed to investigate the epidemiology and risk factors, characteristics, and the rationality of the current therapy for the CRKP infection.

Full description

All the patients with culture positive of Klebsiella pneumoniae were screened and reported to the the clinical doctors and confirmed by them. And the clinical characteristics of the patiens, such as baseline data, outcomes etc, were recorded. Finially, to find the prevalence, risk factors, characteristics, and the rationality of the current therapy for the CRKP infection

Enrollment: 800 estimated patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• new confirmed noscomial infection of CRKP

Exclusion criteria

• Age<18, or >85 years old; Mixed infection of CRKP and other microbes

Trial design

800 participants in 2 patient groups

Carbapenem-Resistant K. pneumoniae

Description:

Patients with clinical confirmed Carbapenem-Resistant Klebsiella pneumoniae infection.

Treatment:

Other: Carbapenem-Resistant Klebsiella pneumoniae

Carbapenem-Sensitive K. pneumoniae

Description:

Any patients with clinical confirmed Carbapenem-Sensitive Klebsiella pneumoniae infection.