Epidemiological, Clinical, Microbiological and Outcome Description of Patients With Klebsiella sp Meningitis (KlebsieLCR)

Fondation Hôpital Saint-Joseph

Status: Completed

Conditions: Meningitis

Study type: Observational

Funder types: Other

Identifiers

NCT03967210

KlebsieLCR

Details and patient eligibility

About

Klebsiella pneumoniae is implicated in the occurrence of severe pneumonia. Most Klebsiella pneumoniae infections are associated with care and occur in patients with compromised immune defenses. More recently, cases of hepatic abscess and acute community meningitis related to strains of Klebsiella pneumoniae have been reported. The mortality of these infections is important, most often due to a delayed diagnosis. The poor prognostic factors reported in the literature for very low numbers are: advanced age, coma, septic shock, glyceryachia <10mg / dL and proteinuria> 750 mg / dL. In addition, no study has specifically focused on the factors of occurrence and factors associated with Klebsiella sp. Indeed, meningitis related to Klebsiella pneumoniae seems to be a rare but probably underestimated event whose risk factors, clinical presentation, microbiological are little known and the treatment modalities of this severe infection are not codified.

Enrollment: 132 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Man or Woman whose age ≥ 18 years
• Patient with meningitis Klebsiella sp., hospitalized in one of the hospitals of the Clinical Microbiology Group
• Francophone patient

Exclusion criteria

• Patient under tutorship or curatorship
• Patient deprived of liberty
• Patient under safeguard of justice
• Patient opposing his participation