Epidemiological Features of Emergent Highly Resistant Bacteria in Tunisian Intensive Care Units (NOSOREA3)

Abderrahmane Mami Hospital

Status: Enrolling

Conditions: Cross Infection; Critical Illness; Vancomycin-Resistant Enterococcal Infection; Carbapenem Resistant Bacterial Infection

Treatments: Other: epidemiological records

Study type: Observational

Funder types: Other

Identifiers

NCT06392568

ATR

Details and patient eligibility

About

Investigate the epidemiology, risk factors and impact on clinical practice of healthcare-associated infections with emergent highly drug-resistant (eHDR) pathogens, particularly carbapenem resistant enterobacteriaceae and glycopeptides-resistant enterococcus.

Full description

In 2022, a previous one-day point-prevalence multicenter study (NOSOREA2, NCT05547646) showed that most prevalent pathogens causing healthcare-associated infections were carbapenem resistant enterobacteriaceae. In 2017, (NOSOREA1, LA TUNISIE MEDICALE - 2018 ; Vol 96 (10/11)), most prevalent pathogens were non-fermenting pathogens.

Faced with this major epidemiological change within Tunisian ICUs, we decided to launch a 3rd survey under the aegis of the 'Association tunisienne de réanimation'. We aimed to investigate the epidemiology, risk factors and impact on clinical practice of healthcare-associated infections with emergent highly drug-resistant (eHDR) pathogens, particularly carbapenem resistant enterobacteriaceae and glycopeptides-resistant enterococcus. So we conducted a multicenter prospective collection that will take place over 2 months.

Enrollment: 500 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult ICU patients admitted during the study period

Exclusion criteria

• none

Trial design

500 participants in 2 patient groups

eHDR+

Description:

Patients with Emergent Highly Resistant Bacteria healthcare associated infection

Treatment:

Other: epidemiological records

eHDR-

Description:

Patients without Emergent Highly Resistant Bacteria healthcare associated infection